HEMEDEX’S BOWMAN PERFUSION MONITOR® SYSTEM:
> Bowman Perfusion Monitor®: a microprocessor-controlled, electronic monitor to collect, store, and display perfusion data
> QFlow 500® Probe: a minimally invasive microprobe
> Fixation Disk: a device for fixing the probe to the scalp
> Umbilical Cord: a cable that connects the probe to the monitor
This platform technology greatly benefits numerous clinical situations where specific, quantitative knowledge of perfusion in real time is crucial.
Hemedex is FDA registered and ISO 13485 certified. Hemedex products are CE marked.
PERFUSION DEFINED
Tissue blood flow, often called perfusion, can be defined as the rate at which the quantity of blood in a given mass or volume of tissue is replenished at the level of the capillary network. Perfusion is a primary factor in the local transport of oxygen, nutrients, waste products, heat, and drugs.
MEASURING PERFUSION
The ability to measure perfusion has been sought after for many years as it is fundamental to improved understanding of both normal and pathologic physiology as well as the diagnosis and management of numerous medical situations including shock and tissue viability subsequent to traumatic injury, transplantation, and non-surgical treatments of cancer.
Many techniques have been proposed and/or pursued as options for quantifying perfusion. These include: positron emission tomography (PET); Xe-CT; magnetic resonance imaging (MRI); radioactive microspheres; laser-doppler flowmetry (LDF); and radioactive tracer washout techniques. Few of these techniques, though, lend themselves to routine clinical application.
PET uses short half-life isotopes, requiring a special facility. MRI, due to its numerous other medical applications, may hold future promise as a qualitative measure of perfusion, but as with PET, it is complex, expensive and does not permit routine monitoring. Radioactive microspheres are suitable for perfusion validation studies in animal models, but are not appropriate for clinical measurements. LDF can provide continuous monitoring; however, the signal depends on a number of factors such as hematocrit, red blood cell velocity, vascular geometry, and tissue optical properties, which vary according to tissue type. As such, it is not currently possible to apply the LDF calibration and measurements from one tissue type to another tissue type. Further, it is unlikely that LDF units can be converted to absolute blood flow in all tissues. LDF may be useful, however, in validating perfusion variation for comparison to other measurement techniques.
Using a proprietary technology in the clinical application of thermal diffusion to measure perfusion, the Bowman Perfusion Monitor® system is the only system that can monitor tissue perfusion continuously, in real time and in absolute physiologic units of ml/100 g-min. And this proprietary technology can be used to develop new products that will address unmet needs in many clinical areas (i.e. neurosurgical monitoring, organ transplantation, cardiovascular monitoring, reconstructive surgery, critical care and endothelial function, etc.).
BOWMAN
PERFUSION MONITOR®
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CLINICAL APPLICATIONS
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QFLOW
500® PROBE
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