QFlow 500 Probe

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  • Probe

    QFlow 500™ Perfusion Probe

     

  • Umbilical Cord and Probe and Dime

    Perfusion Probe is minimally invasive

     

  • Umbilical Cord and Probe Separated on White

    Probe and Umbilical Cord connection

     

  • Fixation – Head and bolt (PROBE page)

    Probe positioned 2.5-3cm below the dura into white matter

     

  • SL bolt with probe

    Perfusion Probe with Single Lumen Bolt

     

  • PPAValueLegendRevisedPPA: Probe Placement Assistant ensures optimal placement

     

When connected to the Bowman Perfusion Monitor®, the minimally invasive QFlow 500™ Perfusion Probe (cat. #H0000-1600) continuously quantifies tissue perfusion in absolute physiological units of ml/100g-min in real time using a thermal diffusion (TD) technique. (To learn more about this technique click here.)

The probe is a flexible, radio-opaque catheter that is inserted into the target tissue where it measures perfusion. The probe is FDA cleared to remain in situ for 10 days.

The probe features placement markings for verification of depth the tissue.

The probe connects to an umbilical cord, which in turn connects to the monitor.  The probe-umbilical and umbilical-monitor interfaces are color-coded to facilitate a connection.

In neurological applications, the probe permits calculation of absolute levels of cerebral blood flow (CBF).

For optimal fixation, secure the probe by using the QFlow 500™ Titanium Bolt Kits.

  • Operates in conjunction with the Bowman Perfusion Monitor®
  • Biocompatible, flexible catheter with a ~1 mm (3 French/19 gauge) diameter
  • CT compatible
  • Centimeter markings for verification of depth.
  • Color-coded to facilitate connection with the umbilical cord
  • Compatible with the QFlow 500™ Titanium Bolts
  • No zeroing or calibration required
  • FDA cleared for 10 days use in situ

How do you insert the Perfusion Probe?

Similar to other brain parenchymal probes, the QFlow 500™ Perfusion Probe is inserted through a burr hole and positioned 2.5-3cm below the dura into white matter.  For optimal fixation Hemedex recommends using the QFlow 500™ Titanium Bolts.

Where do you insert the Perfusion Probe?

The probe should be placed in the vascular territory of interest:

  • In areas which are at risk for ischemia.
  • In watershed area of vessels likely to experience vasospasm.
  • In any area in which you are interested in measuring Cerebral Blood Flow (CBF).

 The probe tip should be completely surrounded by tissue.

Is the Perfusion Probe reusable?

No, the QFlow 500™ Perfusion Probe is a single patient use item.

What is the maximum time a Perfusion Probe can be left in situ?

The probe is indicated for 10 days of use.

Is the Perfusion Probe CT compatible?

Yes.

Is the Perfusion Probe MRI compatible?

No.

Does the local measurement reflect the regional blood flow?

It has been demonstrated in one study that the local perfusion measurements reflect regional changes of flow.

“In this report, we demonstrate that (Thermal Diffusion Flowmetry)TDF allows the assessment of cerebral hemodynamic parameters, such as perfusion and vascular resistance, in patients with SAH and reliably detects the development of vasospasm-associated hypoperfusion. Furthermore, we determine the diagnostic cutoff values, predictive values, and likelihood ratios of TDF for identification of symptomatic vasospasm. Finally, we analyze whether multifocal rCBF monitoring increases diagnostic sensitivity in the identification of symptomatic vasospasm when compared to the use of a single probe.”   “Regional cerebral blood flow monitoring in the diagnosis of delayed ischemia following aneurysmal subarachnoid hemorrhage” Peter Vajkoczy, M.D., Peter Horn, M.D., Claudius Thomé, M.D., Elke Munch, M.D., and Peter Schmiedek, M.D.J. Neurosurg./Volume98/June 2003

However, this probe takes a local (approximately 0.3 ml of tissue) measurement of blood flow, and 
regional flow extrapolation from the local blood flow measurement is not claimed.

How does the probe measure perfusion?

The probe uses a thermal diffusion technique.  For more information click here.

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