Bowman Perfusion Monitor®
The only monitor that continuously measures tissue perfusion in absolute units at the bedside and in the OR.
FDA Cleared
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Our Products
Precision instruments for continuous cerebral perfusion monitoring — from the bedside to the OR
Complete Monitoring System
Every component of the Hemedex system is engineered to work together for accurate, continuous cerebral perfusion measurement
QFlow 500™ Perfusion Probe
A minimally invasive catheter that quantifies tissue perfusion using the proven thermal diffusion technique.
FDA Cleared
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QFlow 500™ Quad Lumen Bolt Kit
Four-channel bolt enabling full multimodal monitoring — CBF, ICP, PbtO₂, microdialysis, and depth electrodes — through a single burr hole.
FDA Cleared
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QFlow 500™ Dual Lumen Bolt Kit
Two-channel configuration supporting any two of CBF, ICP, PbtO₂, microdialysis, and depth electrodes through a single burr hole.
FDA Cleared
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QFlow 500™ Single Lumen Bolt Kit
Dedicated fixation for the QFlow 500™ Perfusion Probe when standalone cerebral blood flow monitoring is the primary goal.
FDA Cleared
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In Development
Product imagery coming soon
Hemodynamic Monitoring & Visualization System (HMVS)
The Bowman Perfusion Monitor delivers clinically meaningful cerebral perfusion data at the bedside. HMVS builds on that foundation, expanding it into a larger, synchronized visual environment for live viewing and longitudinal review.
Learn More
Monitor
Bowman Perfusion Monitor®
The Bowman Perfusion Monitor is the world's only device that continuously and quantitatively measures regional cerebral blood flow in absolute physiological units at the bedside or in the operating room. Designed for extended use in the Neuro ICU, it provides clinicians with a real-time perfusion signal that no other bedside monitor can deliver.
MeasurementAbsolute regional CBF in mL/100 g/min — not a relative index
Monitoring DurationContinuous bedside monitoring for up to 10 days
Clinical SettingNeuro ICU bedside and intraoperative use
DisplayReal-time CBF trending with configurable alarm thresholds
Data OutputCompatible with bedside data management systems
FDA Cleared
Bedside monitoring of perfusion, temperature, and thermal conductivity
Detects changes in blood flow in real-time including onset of ischemia
Provides insight for patient-specific therapy
Detects onset of vasospasm in comatose patients
Helps guide and assess pharmacologic interventions
Permits determination of autoregulation state (with CPP)
Permits determination of cerebral vascular resistance (CVR), shown to predict impending vasospasm
Detects cardiac-induced brain vessel pulsatility
Requires no user calibration or zeroing
IV pole or shelf mountable
Streams measurements via RS‑232 for connectivity to multimodal data systems
User-friendly interface with easy-to-use menu buttons
Prints tabular data and waveforms
Programmable visual/audio alarm
Front display view
Rear panel connections
Frequently Asked Questions
The BPM is primarily used in the Neurointensive Care Unit (SAH, TBI, ICH) and the Operating Room (TAO, AVM, Moya-Moya, EC-IC Bypass).
Tissue temperature: In the process of measuring perfusion, the BPM measures tissue temperature as one of the key variables.
Tissue thermal conductivity (K): K is a proxy for regional tissue water content and has been shown to be a useful indicator of brain edema.*
* Ko et al. "Real Time Estimation of Brain Water Content in Comatose Patients." Annals of Neurology DOI: 10.1002/ana.23619 (2012).
The BPM connects with one probe at a time.
The BPM provides both analog and digital outputs which interface with a number of patient monitors and data acquisition systems.
Digital output interfaces:
- CNS System by CNS Technologies
- Philips-Capsule
- Sickbay
- Moberg Clinical Platform
- ICM+ by University of Cambridge
- Bedmaster by Excel Medical
Analog output interfaces:
- Philips monitors (via VueLink)
- Powerlab by AD Instruments
Yes, current and prior patient data can be reviewed on the screen. Patient data can also be downloaded for review and analysis — Hemedex provides downloading tools. The BPM can store up to 15 days of patient data. We recommend downloading patient data if your monitoring will extend longer than the available time.
Yes, the alarms are disabled by default. Users can enable alarms and set custom limits.
Through the internal printer, you can print:
- Perfusion vs. time plot
- Perfusion and temperature vs. time plots (on the same strip)
- List of Time, K, and PPA values
- Current BPM settings
No manual calibration or zeroing of the BPM is required. The BPM periodically automatically cycles through the 3 measurement phases to update changing patient tissue thermal properties (Conductivity & Diffusivity), which vary with slowly changing levels of edema.
No, the BPM operates on A/C power (110V or 240V, depending on location).
Warranty
Standard 1-year warranty included with the purchase of a Bowman Perfusion Monitor® (BPM).
Hemedex, Inc., warranties this product for a period of 1 year from the date of installation (as evidenced by receipt of warranty card by Hemedex) and technical acceptance by the final customer, limited to parts and labor.
A return authorization number must be obtained from Hemedex, Inc., before returning a unit for repair. Warranty-covered repairs will not be performed without a return authorization number. At the option of Hemedex, Inc., a defective unit will be either repaired or replaced.
Extended warranty options and pricing are available upon request. Contact us for details →
Sensor
QFlow 500™ Perfusion Probe
Designed for direct parenchymal placement, the QFlow 500™ is a minimally invasive, single-use biocompatible perfusion catheter that houses two precision thermistors. The Bowman Perfusion Monitor's thermal diffusion algorithm calculates continuous, absolute CBF values.
TechnologyDual-thermistor Thermal Diffusion Flowmetry (TDF)
DesignMinimally invasive catheter — compatible with standard titanium bolts
SterilitySingle-use, individually sterile packaged
OutputReal-time CBF in absolute units (mL/100 g/min)
FDA Cleared
CT Compatible
Operates in conjunction with the Bowman Perfusion Monitor®
Biocompatible, flexible catheter with a ~1 mm (3 French/19 gauge) diameter
Centimeter markings for verification of depth
Color-coded to facilitate connection with the umbilical cord
Compatible with the QFlow 500™ Titanium Bolts
No zeroing or calibration required
Probe-thermistor detail
Probe and umbilical cord connection
Probe placement video
Frequently Asked Questions
Similar to other brain parenchymal probes, the QFlow 500™ Perfusion Probe is inserted through a burr hole and positioned 2.5–3 cm below the dura into white matter. Hemedex recommends using the QFlow 500™ Titanium Bolts. For ease of insertion at the recommended depth, Hemedex recommends the Probe Dura Piercer and Introducer.
The probe should be placed in the vascular territory of interest:
- In areas which are at risk for ischemia
- In the watershed area of vessels likely to experience vasospasm
- In any area in which you are interested in measuring Cerebral Blood Flow (CBF)
The probe tip should be completely surrounded by tissue.
No, the QFlow 500™ Perfusion Probe is a single patient use item.
The probe is indicated for 10 days of use.
Yes, the probe is CT compatible. The probe is also radio-opaque for imaging verification of placement.
The probe uses a thermal diffusion technique. A heated thermistor warms a small volume of brain tissue, and perfusion carries that heat away. The power required to maintain a fixed thermistor temperature is continuously measured and converted to absolute perfusion values. Learn more about Theory of Operation →
Bolt System — 4 Channels
QFlow 500™ Quad Lumen Bolt Kit
The Universal Quad Lumen Bolt is specifically designed to secure all commonly utilized intraparenchymal sensors, providing four independent lumens through a single burr hole. It supports CBF, ICP, PbtO₂, microdialysis, and depth electrodes.
Multiple peer-reviewed publications confirmed that: ICP, PbtO₂, Temperature, CBF, Conductivity (K), depth electrodes, and microdialysis can all be safely and reliably placed simultaneously via this single-access approach — minimizing procedural risk while maximizing monitoring utility.
Channels4 Independent Lumens
AccessSingle burr hole — reduces procedural risk vs. multiple sites
MaterialMedical-grade titanium — MRI Conditional (up to 3.0T)
Best ForFull MMM panels in severe TBI and SAH
FDA Cleared
Provides access through four ports via one burr hole
Requires no additional tools to insert or remove (other than a drill)
Secures the perfusion probe and three additional probes
Clear lumens to facilitate reading sensor depth markings
MR Conditional for static magnetic field of 3.0T or less
Kit includes 5.3 mm drill bit, depth collar, hex wrench, compression fittings, sealing caps, stylets, sensor introducers, scalpel, pigtail extension, and male-female luer coupler
Quad Lumen Bolt: Sensor-Lumen Compatibility Chart
Perfusion Probe Depth Placement in the Quad Lumen Bolt
Frequently Asked Questions
One lumen accommodates devices < 0.078″ in diameter. Two lumens accommodate devices < 0.064″ (without introducer) or < 0.053″ (with introducers). One lumen accommodates devices < 0.047″ in diameter.
Yes, the bolt is CT compatible.
Yes. All 4 Lumens end with a luer lock, and 3 luer lock-compatible compression fittings are included with the kit.
The bolt is indicated for 14 days of use.
No, the bolt is a single-use item for human clinical purposes.
Introducers are used for delicate sensors (i.e. Microdialysis and Licox catheters) that may need help passing through the dura.
Sealing caps permit the neurosurgeon to place the bolt, which subsequently allows the neurointensivist to later place any number of sensors, as indicated for patient management.
MRI Conditional Safety Information
Non-clinical testing has demonstrated the Hemedex QFlow 500™ Titanium Bolt Kit is MR Conditional. A patient with this device can be safely scanned in an MR system meeting the following conditions:
- Static magnetic field of 3.0T or less
- Maximum spatial field gradient of 8,610 G/cm (86.1 T/m)
- Maximum MR system-reported, whole-body averaged SAR of 2 W/kg (Normal Mode)
Under the scan conditions defined above, the device is expected to produce a maximum temperature rise of less than 0.3°C after 15 minutes of continuous scanning at 1.5T and less than 0.6°C after 15 minutes at 3T.
The image artifact extends approximately 25 mm from the bolt when imaged with a gradient echo pulse sequence and a 3T MRI system.
Note: Prior to transporting to MRI, remove all MR unsafe/conditional sensors. Never leave stylets or MR unsafe sensors in the bolt during MRI. Hemedex recommends lumens be closed/capped following removal of any sensors.
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Bolt System — 2 Channels
QFlow 500™ Dual Lumen Bolt Kit
The Dual Lumen Bolt Kit delivers optimal fixation for the QFlow 500™ Perfusion Probe while providing access for one additional parenchymal sensor. This two-channel configuration supports any two of CBF, ICP, PbtO₂, microdialysis, and depth electrodes — ideal for institutions beginning their multimodal monitoring journey or for cases where a focused two-parameter approach is clinically appropriate.
Channels2 lumens — any two of CBF, ICP, PbtO₂, microdialysis, and depth electrodes
AccessSingle burr hole — two sensors placed through one bolt
MaterialMedical-grade titanium — MRI Conditional (up to 3.0T)
Best ForCBF + ICP monitoring; CBF + brain tissue oxygen monitoring
FDA Cleared
Provides access through two ports via one burr hole
Requires no additional tools to insert or remove (other than a drill)
Secures the perfusion probe and one additional sensor
Clear lumens to facilitate reading sensor depth markings
MR Conditional for static magnetic field of 3.0T or less
Kit includes compression fittings, sealing caps, stylet, sensor introducer, 5.3 mm drill bit with depth collar, hex wrench, scalpel, pigtail extension, and luer coupler
Dual Lumen Bolt: Sensor-Lumen Compatibility Chart
Perfusion Probe Depth Placement in the Dual Lumen Bolt
Frequently Asked Questions
The long lumen accommodates devices < 0.089″ in diameter. The short lumen accommodates devices < 0.053″ in diameter.
Yes, the bolt is CT compatible.
The bolt is indicated for 14 days of use.
Downloads
Bolt System — 1 Channel
QFlow 500™ Single Lumen Bolt Kit
The Single Lumen Bolt Kit provides secure, dedicated fixation for the QFlow 500™ Perfusion Probe when standalone cerebral blood flow monitoring is the primary clinical objective.
Channels1 lumen — dedicated QFlow 500™ probe placement
MaterialMedical-grade titanium — MRI Conditional (up to 3.0T)
Best ForStandalone CBF monitoring
FDA Cleared
Provides single-port access via one burr hole
Requires no additional tools to insert or remove (other than a drill)
MR Conditional for static magnetic field of 3.0T or less
Kit includes 2.7 mm drill bit, depth collar, hex wrench, and dura piercer
Dimensionally Compatible Sensors
| Lumen | Max Diameter | Compatible Sensors |
|---|---|---|
| Single Lumen | 0.060″ (1.5 mm) | QFlow 500™ Perfusion Probe, Depth Electrode, Codman Microsensor ICP, Sophysa ICP (PSO-PTT) |
* Hemedex makes no claims with respect to the functionality and performance of any sensor other than the Hemedex QFlow 500™ Perfusion Probe.
Perfusion Probe Depth Placement in the Single Lumen Bolt
Frequently Asked Questions
Yes, the bolt is CT compatible.
No, the bolt is a single-use item for human clinical purposes.
Yes. Non-clinical testing has demonstrated MR Conditional status under the following conditions:
- Static magnetic field of 3.0T or less
- Maximum spatial field gradient of 8,610 G/cm (86.1 T/m)
- Maximum whole-body averaged SAR of 2 W/kg (Normal Mode)
Maximum temperature rise: < 0.3°C after 15 min at 1.5T; < 0.6°C after 15 min at 3T. Image artifact extends approximately 25 mm from the bolt.
Downloads
Next Generation
In Development
Hemodynamic Monitoring & Visualization System (HMVS)
The Bowman Perfusion Monitor delivers clinically meaningful cerebral perfusion data at the bedside. HMVS builds on that foundation, expanding it into a larger, synchronized visual environment for live viewing and longitudinal review — designed for the modern Neuro ICU and operating room.
StatusCurrently in development
PlatformAdvanced perfusion-based hemodynamic visualization
In Development
Product imagery coming soon
"We report our experience over a 2-year period using a standardized bedside, single burr hole approach to intracranial multimodality monitoring. We were able to safely and consistently measure ICP, oxygenation, regional cerebral blood flow, temperature, and function. This approach generated real-time neuromonitoring data and provides a benchmark for the future use of MMM to guide a precision-medicine approach to the clinical management of patients with severe acute neurological injuries, such as TBI."
Brandon Foreman et al., "Safety and Reliability of Bedside, Single Burr Hole Technique for Intracranial Multimodality Monitoring in Severe Traumatic Brain Injury," Neurocrit Care, 2018 Dec;29(3):469-480.
doi.org/10.1007/s12028-018-0551-7 →
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